1 stay of 30 nights & 3 follow up visits

8448-214 Part B 4b 4b

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1 stay of 30 nights & 3 follow up visits

Study Number

8448-214 Part B 4b






21 - 60


Madison, Wisconsin



Study Dates

Mar. 12 - May 08, 2023

Additional Information

This is a research study for an investigational drug being developed for the treatment of hypoparathyroidism, a condition where the parathyroid gland (4 small glands in the neck) does not produce enough parathyroid hormone which causes low calcium levels in the blood. This is the first time the study drug will be given to humans.

The purpose of this study is to evaluate the safety and tolerability (side effects) of single and multiple doses of the study drug at gradually increasing dose levels. The study will also measure how much of the study drug gets into the bloodstream, and how long it takes the body to get rid of it. In addition, the effect of the study drug on certain hormones, proteins, and minerals in the body will be measured.

Part B

You will receive 4 doses of the study drug or placebo (inactive drug) as a subcutaneous (under the skin) injection in the abdomen. The injection sites will be rotated in the abdomen.

Labcorp Madison, WI is recruiting for:

- Healthy Males and Females of Non-Childbearing Potential, age 21-60

- Body Mass Index between 20-32

- Study involves 1 stay of 30 nights, plus 3 follow-up visits

- Compensation up to $15,075 may be provided for time and participation - Receive up to $200 per qualified participant


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Check in: Mar 12

Check out: Apr 11

OPVs: Apr 18, Apr 24, May 8

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